Decreased expression of the human stem cell marker, Rex-1 (zfp-42) , in renal cell carcinoma

Decreased expression of Dkk1 and Dkk3 in human clear cell renal cell carcinoma.

The expression patterns of the Dickkopf (Dkk) family of proteins varies in different cancers. In the present study, the expression levels of Dkk1 and Dkk3 were investigated in clear cell renal cell carcinoma (ccRCC) tissues. Dkk1 and Dkk3 serum levels were also examined in patients with ccRCC, and the association between clinicopathological features and Dkk levels was investigated. Serum Dkk1 a...

Sarcomatoid Transrormation of Chromophobe Renal Cell Carcinoma

Dyspnea as the First Manifestation of Silent Renal Cell Carcinoma

Renal cell carcinoma (RCC) accounts for only 3% of adult malignancies, and the lung is the most common site of metastasis of this tumor, which may be accompanied by pleural metastasis. However, solitary pleural involvement is very rare and its presentation with dyspnea as the first manifestation of RCC is extremely rare.We describe a 39-year-old male with episodes of dyspnea dating back 6...

Expression Of P53 And Ki67 Proteins In Renal Cell Carcinoma And Its Relationship With Nuclear Grade

Background and Objective: Evaluation of tumor proliferative activity may provide a predicting parameter to estimate biologic aggression and a subsequent prognosis that has been evaluated in many malignancies. We have selected renal cell carcinoma (RCC) in this study. To determine tumor proliferative activity, KI67 antibody was applied and results were compared with apoptosis, applying P53 antib...

Expression of claudins in human clear cell renal cell carcinoma.

The current study investigated the expression of claudins 1, 5 and 16 in human clear cell renal cell carcinoma (CCRCC) and the impact of claudin-16 on kidney cancer cells. Levels of claudin transcripts were assessed using quantitative reverse transcription-polymerase reaction and proteins were examined by immunohistochemical methods. Human kidney epithelial cell HEK293 and human kidney cancer c...